Kimmel often touched on politics in his speech although many people suggested that he should steer clear.
"This broadcast is being watched live by millions of Americans and around the world in more than 225 countries that now hate us. And I think that is an amazing thing," joked Kimmel. "As you know, I don't have to tell anybody, the country is divided right now. I've been getting a lot of advice. People have been telling me it's time to bring everyone together, you need to say something to unite us, and let's just get something straight off the top. I'n not I can't do that. There's only one Braveheart in this room and he's not going to unite us either, okay?Mel, you look great, I think the Scientology is working. I really do."
Kimmel also took a serious moment to give hope and advice to the millions of Americans watching.
"I'm not the man to unite this country, but it can be done," said Kimmel. "You know, if every person watching this show I don't want to get too serious but there are millions and millions of people watching right now. And if every one of you took a minute to reach out to one person you disagree with, someone you like and have a positive considerate conversation, not as liberals or conservatives, as Americans. If we would all do that, we could make America great again. It starts with us."